Central | US 20 / WY 789 | | Mile Marker 148, Washakie/Hot Springs County Line | Thermopolis |
US 26 | | Diversion Dam Jct | Riverton |
US 287 | | Lander | Diversion Dam Jct |
US 287 / WY 789 | | Sweetwater Station Jct | Jct WY 28 / US 287 |
| Jct WY 28 / US 287 | Lander |
WY 132 | | US 287 | Ethete |
| Ethete | US 26 |
WY 789 | | Lander | Hudson |
Northeast | I 90 | | Sheridan | Exit 44, Piney Creek Rd |
| the Johnson/Campbell County Line | Gillette |
| Exit 165, Pine Ridge Rd | Sundance |
I 90 Business | | Sundance | South Dakota State Line |
I 90 / US 14 | | Sundance | the South Dakota State Line |
I 90 / US 14/16 | | Gillette | Rozet |
I 90 / US 14/87 | | Ranchester | Sheridan |
I 90 / US 87 | | the Montana State Line | Ranchester |
US 14 | | Antelope Butte Mountain Recreation Area | Elk View |
| Elk View | Steamboat Rock |
| Steamboat Rock | Dayton School |
| Dayton | Ranchester |
| Sheridan | Ucross |
| Carlile | WY 24 |
| WY 24 | Sundance |
US 14/16 | | Mile Marker 60, the Sheridan/Campbell County Line | WY 59 |
US 16 | | Worland | Ten Sleep |
| Ten Sleep | WY 435 |
| WY 435 | Deer Haven Lodge |
| Deer Haven Lodge | Canyon Creek Rd |
| Canyon Creek Rd | Sheep Mountain Rd |
| Sheep Mountain Rd | Hunter Ranger Station |
| Hunter Ranger Station | Buffalo |
| Buffalo | Ucross |
| Upton | Newcastle |
| Mile Marker 249 | Mile Marker 254, Eastbound Closure Gate |
| Mile Marker 254, Eastbound Closure Gate | the South Dakota State Line |
US 16 Bypass | | Mile Marker 247 | Mile Marker 249 |
US 85 | | Newcastle | WY 585, Four Corners |
WY 110 | | WY 24 | Devils Tower Nat'l Monument |
WY 111 | | Aladdin | I-90 |
WY 112 | | Hulett | Strawberry Hill |
| Strawberry Hill | the Montana State Line |
WY 116 | | Sundance | Upton |
WY 193 | | Kearny | Banner |
WY 194 | | Story | End of State Route |
WY 24 | | US 14 | Hulett |
| Hulett | the east side of Bear Lodge |
| the east side of Bear Lodge | the South Dakota State Line |
WY 332 | | Sheridan | WY 334 |
WY 336 | | Sheridan | Dutch Creek Rd |
WY 338 | | Sheridan | the Montana State Line |
WY 340 | | Story | North Piney Creek |
WY 343 | | WY 345 | Dayton |
WY 345 | | the Montana State Line | Ranchester |
| Ranchester | I-90 |
WY 387 | | Pine Tree Jct | Wright |
| Wright | Reno Jct |
WY 450 | | Newcastle | WY 116 |
| the Campbell/Weston County Line | Mile Marker 54, Eastbound Closure Gate |
| Mile Marker 54, Eastbound Closure Gate | WY 59 |
WY 585 | | Crook/Weston County Line | Sundance |
| Four Corners | Crook/Weston County Line |
WY 59 | | the Campbell/Converse Cty Line | Mile Marker 67, Edwards Rd |
| Mile Marker 67, Edwards Rd | Wright |
| Wright | Mile Marker 94, Haight Rd |
Northwest | US 14 | | Greybull | Shell |
US 14/16/20 | | Pahaska | the Shoshone National Forest Boundary |
| the Big Horn County Line | 4 miles west of Greybull |
US 14/16/20/310 / WY 789 | | Greybull | 4 miles west of Greybull |
US 14 A | | Powell | the West Jct US 310 / WY 789 |
| Lovell | 22 miles east of Lovell |
US 14A/310 | | Lovell | the West Jct US 310 / WY 789 |
US 16/20 / WY 789 | | Greybull | Basin |
| Basin | Manderson |
US 189/191 | | Bondurant | Hoback Jct |
US 26/287 | | Dubois | Diversion Dam Jct |
US 310 / WY 789 | | 4 miles west of Greybull | Lovell |
| US 310 / WY 789 | the Montana State Line |
WY 114 | | Garland | Deaver |
WY 22 | | Wilson | the Idaho State Line |
WY 431 | | US 20 / WY 789/432 | WY 120 |
Southeast | I 80 | | Exit 279, Cooper Cove Rd | Exit 290, Quealy Dome |
I 80 / US 30 | | Laramie | Exit 323, Happy Jack Rd |
| Exit 323, Happy Jack Rd | Exit 335, Buford |
US 26 | | Guernsey | Lingle |
| Torrington | the Nebraska State Line |
US 26/85 | | Torrington | Lingle |
US 287 | | the Colorado State Line | Start of Divided Highway, Mile Marker 416 |
| Start of Divided Highway, Mile Marker 416 | Mile Marker 413, 4 Miles North of Tie Siding |
US 30/287 | | Medicine Bow | Rock River |
US 85 | | Meriden | WY 151, Bear Mountain Station |
| WY 151, Bear Mountain Station | WY 161, Silvertip |
| WY 161, Silvertip | Torrington |
| Lingle | Jay Em |
WY 10 | | Woods Landing | the Colorado State Line |
WY 11 | | WY 130 | Albany |
WY 12 | | WY 130 | Mandel Lane |
WY 13 | | Rock River | Arlington |
WY 130 | | I-80, Walcott Jct | WY 230 |
| WY 230 | Mile Marker 48, Eastbound Closure Gate |
| Green Rock | Centennial |
| Centennial | WY 130/230 |
WY 210 | | Curt Gowdy State Park | I-80 |
WY 212 | | College Dr | WY 219, Yellowstone Rd |
WY 213 | | I-80 | US 85 |
WY 214 | | I-80 | Carpenter |
WY 215 | | Pine Bluffs | Albin |
WY 216 | | US 85 | the Nebraska State Line |
WY 230 | | the Colorado State Line | Woods Landing |
| Woods Landing | Laramie |
WY 313 | | Chugwater | US 85 |
WY 72 | | I-80 | Hanna Jct |
Southwest | I 80 | | Exit 18, US 189 | Exit 30, Bigelow Rd |
| Exit 30, Bigelow Rd | Exit 39, WY 412/414 |
| Exit 39, WY 412/414 | MM 57, Sweetwater County Line |
| MM 57, Uinta County Line | Exit 66, Granger Jct |
I 80 / US 189 | | the Utah State Line | Evanston |
| Evanston | Exit 18, US 189 |
I 80 / US 30 | | Exit 66, Granger Jct | Exit 83, La Barge Rd |
| Exit 83, La Barge Rd | Exit 91, Flaming Gorge Way |
| Exit 91, Flaming Gorge Way | Exit 104, Rock Springs |
| Exit 104, Rock Springs | Exit 111, Airport and Baxter Roads |
| Point of Rocks | Exit 142, Bitter Creek |
| Exit 142, Bitter Creek | Exit 158, Tipton Rd |
US 189 | | I-80 | WY 412 |
| WY 412 | Kemmerer |
| Kemmerer | WY 372 |
| WY 372 | La Barge |
| La Barge | Big Piney |
US 189/191 | | Daniel Jct | Bondurant |
US 191 | | Rock Springs | Mile Marker 12, Yellowstone Rd |
| Mile Marker 12, Yellowstone Rd | Farson |
| Farson | WY 351 |
| Pinedale | Daniel Jct |
US 26 | | the Idaho State Line | Alpine Jct |
US 30 | | Mile Marker 38, County Rd 209 | Kemmerer |
| Kemmerer | Opal |
| Opal | I-80, Granger Jct |
US 30 / WY 89 | | Border Jct | Cokeville |
| Border Jct | the Idaho State Line |
US 89 | | Afton | Alpine Jct |
WY 233 | | Kemmerer | End of State Route |
WY 235 | | La Barge | Calpet |
WY 240 | | Opal | US 189 |
WY 28 | | WY 372 | Farson |
| Farson | the Fremont/Sublette Cty Line |
| Mile Marker 47 | Mile Marker 63, Westbound Closure Gate |
WY 350 | | Big Piney | End of State Route |
WY 352 | | US 191 | Bridger Teton Nat'l Forest |
WY 353 | | US 191 | End of State Route |
WY 372 | | I-80 | WY 28 |
| WY 28 | US 189 |
WY 374 | | I-80 | US 30 |
| I-80, Little America | WY 372 |
| WY 372 | Green River |
WY 410 | | Mountain View | End of State Route |
WY 411 | | WY 410 | Millburne |
WY 530 | | Green River | the Utah State Line |
WY 789 | | Mile Marker 25 | I-80, Creston Junction |
WY 89 | | Evanston | the Utah State Line |